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难以忍受的头疼，恶心，口干舌燥，疲劳,颤抖还伴随着天旋地转――当你醒来时是不是感觉昨晚喝得有点多了呢？宿醉可不是好玩的,但是有大量的”治疗方法”存在--从推荐的“狗毛”（含有更多的酒精）到冷披萨。但是这里面几乎没几个经过科学分析。因此，真正的药方在哪里？
位于英国埃克塞特和普利茅斯的大学的半岛医疗学校研究人员们检索了医药数据库和因特网，并为了预防和治疗宿醉的随机控制试验联系专家和生产者。
他们用八个试验测试八个不同的代理机构：心得安（一种β受体阻滞剂），龙骨瓣（一种治疗头晕恶心的药）tolfenamic 酸（一种止疼药）,果糖或是葡萄糖，还有随饭补充的琉璃苣，朝鲜蓟,仙人掌果，还有一个酵母制备物。
大多数试验现实没有任何的好处，虽然琉璃苣中提出的三亚麻酸，酵母制备物和tolfenamic酸显示出微弱的效果，但是就研究人员Edzard Ernst来说，这些都不足以证明他们有效。
他还说，一系列的测试的治疗显示我们对宿醉的机制还缺乏了解。
Ernst说他认为药方不会被找到，并且寻找药方还涉及到一个道德问题：“这将引导人们喝得更多，因为他们认为药方会减小伤害。”
他说“宿醉是自然在告诉人们酒精是有害的，并且避免宿醉的最有效的方式是戒酒和适度饮酒。”
Hunting a cure for the holiday hangovers
11:27 23 December 2005
NewScientist.com news service
Gaia Vince
Thumping headache, nausea, parched mouth, tired and shaky with room-spinning dizziness – ever woken up with the feeling that you may have drunk a bit too much alcohol the night before? Hangovers are not fun, but a plethora of “cures” exist – from recommendations of “hair of the dog” (more alcohol) to cold pizza. But few of these have been subjected to scientific analysis. So is there a real cure?
Researchers from Peninsula Medical School at the universities of Exeter and Plymouth in the UK searched medical databases and the internet, and contacted experts and manufacturers for randomised controlled trials of any medical intervention for preventing or treating alcohol hangover.
They found eight trials testing eight different agents: propranolol (a beta-blocking drug), tropisetron (a drug for nausea and vertigo), tolfenamic acid (a painkiller), fructose or glucose, and the dietary supplements borage, artichoke, prickly pear, and a yeast based preparation.
Do you have your own foolproof hangover cure? Tell us...
Discuss this story >> The majority of trials showed no beneficial effects, although three – linolenic acid extracted from borage, the yeast-based preparation, and tolfenamic acid – “seemed to show some slight effect, although it is premature to confirm this”, according to Edzard Ernst, who carried out the research.
“The range of treatments tested show that there is a lack of understanding of what is mechanistically behind a hangover,” he adds.
Ernst says that he thinks it is unlikely a cure will be found, and points out the ethical issues involved in finding one: “It could lead to people drinking more alcohol because they think it is harmless.
“A hangover is nature’s way of saying alcohol is bad for you,” he says, adding: “the most effective way to avoid the symptoms of a hangover is to practice abstinence and moderation.”
Journal reference: British Medical Journal (vol 331, p 1515)
帖子在2005-12-29 8:20:18被编辑过了 | 最初发表时间：2005-12-28 |  | | 未填 |
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